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Highlord Darion Mograine wants you to infuse Shadow's Edge with blood and defeat Queen Lana'thel. This quest may only be completed in 25 person difficulty of Icecrown Citadel. This quest starts and ends in Icecrown Citadel.
Your weapon is ready to be endowed with the power of blood. You must face Queen Lana'thel in battle and subject yourself to her Blood Mirror. This will cause Shadow's Edge to drink the blood of the nearest living being. That being would be you. Once the blade has been thus awakened, allow the Queen's Frenzied Bloodthirst to take hold of you, feed the blade thrice to sate it, and then give the queen an ignominious death. May her screams pierce the ears of the Lich King as he awaits his fate.
Here you can buy Blood infusion quest boost for EU or US Servers.
Also you'll get guide for completing Blood infusion quest
You“ll be able to complete one of the quests for Legendary Shadowmourne quests chain
Knowledge how to do it
350 reputation with the Ashen Verdict
Completing the quest "Blood infusion"